Clinicopathologic significance of GLUT1 expression and its correlation with Apaf-1 in colorectal adenocarcinomas

doi:10.3748/wjg.v17.i14.1866

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 14, 2011; 17(14): 1866-1873
Published online Apr 14, 2011. doi: 10.3748/wjg.v17.i14.1866

Table 1 Glucose transporter 1 expression in normal mucosa, tubular adenomas, adenocarcinomas, and metastatic lesions (n = 718)

Tissue samples	n	Expression of GLUT1				P value
Tissue samples	n	Negative (%)	Low (%)	Moderate (%)	High (%)	(χ²-test)
Normal mucosa	26	26 (100.0)	0 (0.0)	0 (0.0)	0 (0.0)	< 0.001¹
Tubular adenomas with LGD	26	21 (80.8)	5 (19.2)	0 (0.0)	0 (0.0)
Tubular adenomas with HGD	24	10 (41.7)	9 (37.5)	5 (20.8)	0 (0.0)
Adenocarcinomas	515	92 (17.9)	75 (14.6)	161 (31.2)	187 (36.3)
Metastatic lesions	127	31 (24.4)	15 (11.8)	22 (17.3)	59 (46.5)

¹: χ² test for linear trend. LGD: Low grade dysplasia; HGD: High grade dysplasia; GLUT1: Glucose transporter 1; Metastatic lesions; lymph nodes and distant organs.

Citation: Jun YJ, Jang SM, Han HL, Lee KH, Jang KS, Paik SS. Clinicopathologic significance of GLUT1 expression and its correlation with Apaf-1 in colorectal adenocarcinomas. World J Gastroenterol 2011; 17(14): 1866-1873
URL: https://www.wjgnet.com/1007-9327/full/v17/i14/1866.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i14.1866