Omeprazole decreases magnesium transport across Caco-2 monolayers

Table 2 Electrical parameters of Caco-2 monolayers

	n	PD (mV)	ISC (mA/cm2)	TER (Ω.cm2)
14 d
Control	9	0.99 ± 0.12	3.09 ± 0.36	322.19 ± 6.37
Omeprazole treated (ng/mL)
200	9	1.03 ± 0.54	2.52 ± 0.39	413.64 ± 12.95
400	9	0.98 ± 0.14	2.24 ± 0.29	433.23 ± 17.66
600	9	1.08 ± 0.15	2.29 ± 0.31	470.35 ± 23.87d
800	9	1.09 ± 0.18	2.30 ± 0.41	483.22 ± 20.20d
1000	9	1.20 ± 0.11	2.41 ± 0.20	502.88 ± 30.99d
21 d
Control	9	1.00 ± 0.15	3.18 ± 0.47	314.05 ± 4.64
Omeprazole treated (ng/mL)
200	9	1.26 ± 0.20	2.48 ± 0.32	485.09 ± 24.36b
400	9	1.13 ± 0.19	2.20 ± 0.32	502.19 ± 27.47d
600	9	1.06 ± 0.13	2.21 ± 0.34	500.33 ± 32.97d
800	9	0.99 ± 0.19	1.97 ± 0.31	481.64 ± 25.48d
1000	9	1.07 ± 0.18	2.06 ± 0.30	500.84 ± 26.61d

^bP < 0.01,

^dP < 0.001 vs the age-matched control group.