Brief Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 14, 2011; 17(10): 1362-1367
Published online Mar 14, 2011. doi: 10.3748/wjg.v17.i10.1362
Table 2 Genotype and allele frequencies of interleukin-10 promoter SNP in gastric cancer patients and controls
Genotypes/alleleCasesn (%)Controlsn (%)Adjusted OR (95% CI)1P
IL-10-1082234243
AA189 (80.4)217 (89.3)1
AG39 (17.2)23 (9.7)1.9 (1.1-3.4)0.019a
GG6 (2.4)3 (1.0)2.4 (0. 6-9.4)0.244
A417 (89.1)457 (94.0)1
G51 (10.9)29 (6.0)1.2 (0.6-3.2)0.007a
IL-10-819
TT99 (42.3)109 (44.9)1
TC96 (41.0)106 (43.6)0.9 (0.7-1.6)0.975
CC39 (16.8)28 (11.5)1.6 (0.9-2.8)0.145
T294 (62.8)324 (66.7)1
C174 (37.2)162 (33.3)1.2 (0.9-1.6)0.221
IL-10-592
AA99 (42.3)109 (44.9)1
AC96 (41.0)106 (43.6)0.9 (0.7-1.6)0.975
CC39 (16.8)28 (11.5)1.6 (0.9-2.8)0.145
A294 (62.8)324 (66.7)1
C174 (37.2)162 (33.3)1.2 (0.9-1.6)0.221
Haplotype
ATA282 (60.3)314 (64.6)1
ACC135 (28.9)143 (29.4)1.1 (0.8-1.5)0.731
GCC39 (8.3)19 (3.9)2.3 (1.2-4.1)0.005a
GTA12 (2.5)10 (2.1)1.3 (0.6-3.2)0.504