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©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 14, 2011; 17(10): 1317-1325
Published online Mar 14, 2011. doi: 10.3748/wjg.v17.i10.1317
Published online Mar 14, 2011. doi: 10.3748/wjg.v17.i10.1317
Table 2 Median relative difference1 in receptor expression and cytokine secretion by peripheral blood mononuclear cells of non-cirrhotic and cirrhotic patients after exposure to lipopolysaccharide and lipoteichoic acid
Non-cirrhotic (%) | Cirrhotic (%) | P value | ||
n = 10 | n = 10 | |||
Expression | ||||
CD14 | LPS | -9 | +39 | < 0.096b |
LTA | -3.50 | +55 | < 0.028a | |
TLR2 | LPS | -10 | -60 | < 0.121 |
LTA | 0 | -42 | < 0.289 | |
TLR4 | LPS | 30 | -53 | < 0.221 |
LTA | -19.50 | -29 | < 0.935 | |
Secretion | ||||
TNFα | LPS | +7400 | +8770 | < 0.940 |
LTA | +190 | +360 | < 0.970 | |
IL-1β | LPS | +70.50 | +1164 | < 0.019a |
LTA | -6 | +71 | < 0.049a | |
IL-6 | LPS | +91 | +319 | < 0.174 |
LTA | +125 | +246 | < 0.326 | |
IL-12 | LPS | +3324 | +6219 | < 0.151 |
LTA | +503 | +1786 | < 0.227 | |
IL-10 | LPS | +1768 | +5844 | < 0.364 |
LTA | +50 | +415 | < 0.571 |
- Citation: Barbero-Becerra VJ, Gutiérrez-Ruiz MC, Maldonado-Bernal C, Téllez-Avila FI, Alfaro-Lara R, Vargas-Vorácková F. Vigorous, but differential mononuclear cell response of cirrhotic patients to bacterial ligands. World J Gastroenterol 2011; 17(10): 1317-1325
- URL: https://www.wjgnet.com/1007-9327/full/v17/i10/1317.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i10.1317