MiRNA profile in esophageal squamous cell carcinoma: Downregulation of miR-143 and miR-145

Figure 1 miRNAs are deregulated in esophageal squamous cell carcinoma as detected by microRNA microarray. Three pairs of esophageal carcinoma and normal tissue matches were analyzed by miRCURY LNA™ microRNA Arrays v.11.0. Each RNA sample was dye-swap labeled. Unsupervised hierarchical cluster analysis of miRNA expression in three esophageal carcinoma patients. Rows: miRNAs; columns: cases. The analysis showed that two chips in each case were consistent. For each miRNA, red represents higher expression and blue represents lower expression than the average expression. S1, sample 1; S2, sample 2; S3, sample 3.