Mindin is upregulated during colitis and may activate NF-κB in a TLR-9 mediated manner

Figure 1 Mindin mRNA expression is upregulated during acute intestinal inflammation. A: Histological analysis of normal tissue and of acute inflammation specimen after 6 d of DSS. HE staining of colonic sections (magnification 40 ×); B: Quantitative mRNA expression of mindin in study mice (left graph, n = 3 of each group, triplicate samples from each mouse, right graph combines the data from each group); C: Relative mRNA expression of NF-κB p65 in study groups. Bars represent mean ± SD; ^bP < 0.01 vs day 0.