Pathological differential diagnosis of solid-pseudopapillary neoplasm and endocrine tumors of the pancreas

Figure 2 β-catenin oncogene mutations in SPN. Representative DNA sequencing chromatograms demonstrate. A: A GAC→TAC mutation in codon 32 of case 5; B: A TCT→TAT mutation in codon 37 of case 2; C: A GAC→GTC mutation in codon 32 of case 9. Three samples of PET cases were randomly selected to be sequenced and the results confirmed that there was not any mutation on amplified PCR fragments of β-catenin gene exon 3.