Preparation, physicochemical characterization and cytotoxicity in vitro of gemcitabine-loaded PEG-PDLLA nanovesicles

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Feb 28, 2010 (publication date) through Feb 4, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 28, 2010; 16(8): 1008-1013
Published online Feb 28, 2010. doi: 10.3748/wjg.v16.i8.1008

Table 2 The inhibitory effect of Gemcitabine-loaded nanovesicles and free gemcitabine on human SW1990 pancreatic cancer cells

Drug concentration (mol/L)	Gemcitabine-loaded nanovesicles	Free gemcitabine	P value
	Cell inhibitory rate (%)	Cell inhibitory rate (%)
10^-7	18.3 ± 1.6	21.7 ± 2.5	0.480
10^-6	46.2 ± 2.7	49.5 ± 4.1	0.619
10^-5	82.3 ± 5.4	78.8 ± 4.2	0.592
10^-4	93.2 ± 5.3	95.2 ± 3.7	0.552

Citation: Jia L, Zheng JJ, Jiang SM, Huang KH. Preparation, physicochemical characterization and cytotoxicity in vitro of gemcitabine-loaded PEG-PDLLA nanovesicles. World J Gastroenterol 2010; 16(8): 1008-1013
URL: https://www.wjgnet.com/1007-9327/full/v16/i8/1008.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i8.1008