Analgesic effects of JCM-16021 on neonatal maternal separation-induced visceral pain in rats

Figure 1 Pain threshold pressure assessment in different groups. Data are presented as the mean ± SE. Before treatment, the pain threshold of NMS groups was significantly decreased, as compared with that of the NH-VH group (^bP < 0.001). After treatment, JCM-16021 and Holopon significantly increased the pain threshold pressure (^aP < 0.05, ^dP < 0.01, ^fP < 0.001) compared with that before treatment of each group.