Etiological and clinicopathologic characteristics of intrahepatic cholangiocarcinoma in young patients

Table 3 Comparison of pathological features of ICC between the two groups n (%)

	Group I (n = 40)	Group II (n = 277)	P value
Tumor location			0.827
Right lobe	25 (6.25)	160 (57.76)
Left lobe	14 (35.00)	111 (40.07)
Both lobes	1 (2.50)	6 (15.00)
Tumor size (cm)	6.80 ± 3.92	6.67 ± 3.38	0.892
Tumor number			0.474
1	36 (90.00)	258 (93.14)
≥ 2	4 (10.00)	19 (6.86)
Histological inflammation	15 (37.50)	47 (16.97)	0.002
Capsule	5 (12.50)	35 (12.64)	0.981
Tumor differentiation			0.506
Well	0 (0.00)	9 (3.25)
Moderate	29 (72.50)	191 (68.95)
Poor	11 (27.50)	71 (25.63)
Microvascular invasion	10 (25.00)	41 (14.80)	0.101
Perineural infiltration	0 (0.00)	4 (1.44)	0.444
Portal vein invasion	3 (7.50)	30 (10.83)	0.519
Lymphatic metastasis	8 (20.00)	46 (16.61)	0.594
Microscopic satellite lesion	7 (17.50)	69 (24.91)	0.305
Immunohistochemical examinations
Ck18 positive	38 (95.00)	269 (97.11)	0.475
Ck19 positive	40 (100.00)	267 (93.39)	0.222

Ck: Cytokeratin.