Etiological and clinicopathologic characteristics of intrahepatic cholangiocarcinoma in young patients

Table 2 Comparison of clinical features of ICC between the two groups n (%)

	Group I (n = 40)	Group II (n = 277)	P value
Gender (M/F)	30/10	193/84	0.491
ALT (> 42 U/L)	15 (60.00)	89 (32.13)	0.499
AST (> 37 U/L)	12 (30.00)	103 (37.18)	0.377
TBIL (> 20 μmol/L)	7 (17.50)	62 (22.38)	0.484
Albumin (g/L)	43.82 ± 4.27	42.07 ± 5.12	0.236
GGT (> 64 U/L)	19 (47.50)	176 (63.54)	0.051
ALP (> 119 U/L)	15 (11.19)	134 (48.38)	0.198
AFP (> 400 μg/L)	7 (17.50)	17 (6.14)	0.011
CA19-9 (> 37 U/mL)	14 (35.00)	153 (55.23)	0.017

M: Male; F: Female; TBIL: Total bilirubin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; AFP: α-fetoprotein; ALP: Alkaline phosphatase; r-GT: r-glutamyl-transferase; CA 19-9: Carbohydrate antigen 19-9. Group I: ICC patients aged ≤ 40 years; Group II: ICC patients aged > 40 years.