Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice

Figure 1 Effect of 25 μg Schistosoma mansoni soluble worm (SmSWP) proteins on clinical disease score (A), macroscopic score (B), extent of inflammation (C), microscopic score (D) and myeloperoxidase (MPO) activity (E) 5 d after trinitrobenzene sulphate (TNBS)-induced colitis. Grey bars represent phosphate-buffered saline (PBS)-treated TNBS mice; black bars represent SmSWP-treated TNBS mice. Data are presented as mean ± SE. Non-parametric data (A, B, D) were analyzed by the Mann-Whitney U test, parametric data (C, E) were analyzed by the Student’s t-test; n = 8-10; ^aP≤ 0.05, significant effect of SmSWP treatment.