DNA polymorphism and risk of esophageal squamous cell carcinoma in a population of North Xinjiang, China

Table 2 Analysis of genes allele in ESCC carcinogenesis

Gene	Locus	Control allele frequency (n = 326)		Case allele frequency (n = 128)		OR (95% CI)	P value
		1	2	1	2
ALDH2	Rs886205	448	204	200	56	1.626 (1.158-2.284)	0.005
XPD	Rs50872	522	130	187	69	1.482 (1.058-2.074)	0.022
MGMT	Rs7069143	356	296	162	94	0.698 (0.518-0.939)	0.017
MGMT	Rs3793909	535	117	224	32	0.653 (0.429-0.995)	0.046
MGMT	Rs12771882	165	487	82	174	0.719 (0.524-0.986)	0.040
MGMT	Rs551491	280	372	132	124	0.707 (0.529-0.945)	0.019
MGMT	Rs11016879	264	388	136	120	1.666 (1.245-2.228)	0.001
MGMT	Rs7071825	415	237	139	117	0.618 (0.506-0.910)	0.009