Significance and relationship between Cripto-1 and p-STAT3 expression in gastric cancer and precancerous lesions

Table 1 Expression of CR-1 protein in normal gastric mucosa, chronic atrophic gastritis, intestinal metaplasia, dysplasia and GC

Groups	n	CR-1 expression				+→+++ (%)	χ²	P
		-	+	++	+++
Normal mucosa	95	54	23	11	7	43.2	8.394/25.813	< 0.039a/< 0.001b
CAG	40	14	11	12	3	65.0	4.214/4.192	0.239c/0.242d
IM	48	8	18	19	3	83.3	9.169	0.027e
DYS	25	5	13	6	1	80.0	13.051/4.135	0.005f/0.246g
GC	178	51	63	38	26	71.3	21.236/3.347	< 0.001h/0.341i

^aNormal mucosa vs CAG;

^bNormal mucosa vs IM;

^cCAG vs IM;

^dCAG vs DYS;

^eIM vs GC;

^fNormal mucosa vs DYS;

^gDYS vs GC;

^hNormal mucosa vs GC;

ⁱCAG vs GC. CR-1: Cripto-1; GC: Gastric cancer; CAG: Chronic atrophic gastritis; IM: Intestinal metaplasia; DYS: Dysplasia.