A systematic review of efficacy and tolerability of mebeverine in irritable bowel syndrome

Table 3 Outcome results of studies comparing mebeverine with placebo included in meta-analysis

Study	Adverse effect		Relief of abdominal pain		Global or clinical improvement
	Placebo	Mebeverine	Placebo	Mebeverine	Placebo	Mebeverine
Kruis et al[21] 1986	-	-	11/40	9/40	12/40	6/40
Connell[13] 1965	3/22	2/22	-	-	1/22	11/22
Tasman-Jones[22] 1973		-	7/24	15/24	7/24	15/24
Berthelot et al[11] 1981	-	-	-	-	24/33	31/36
Secco et al[19] 1983	-	-	9/15	12/15	-	-
Enck et al[23] 2005	-	-	-	-	16/40	8/40