Impaired PI3K/Akt signal pathway and hepatocellular injury in high-fat fed rats

doi:10.3748/wjg.v16.i48.6111

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Dec 28, 2010 (publication date) through Jan 23, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 28, 2010; 16(48): 6111-6118
Published online Dec 28, 2010. doi: 10.3748/wjg.v16.i48.6111

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Figure 2 Ultrastructural changes in hepatocellular mitochondria. A: Mitochondria (a) in normal diet group; B: Enlarged mitochondria (b) and lipid droplet (c) in high-fat diet group; C and D: Animals treated with either phosphatidylinositol 3-kinase blocker (C) or protein kinase B blocker (D) showed similar changes in mitochondrial shape, size (d, f) and lipid droplet (e, g) to those of the high-fat group. Magnification × 18 000.

Citation: Han JW, Zhan XR, Li XY, Xia B, Wang YY, Zhang J, Li BX. Impaired PI3K/Akt signal pathway and hepatocellular injury in high-fat fed rats. World J Gastroenterol 2010; 16(48): 6111-6118
URL: https://www.wjgnet.com/1007-9327/full/v16/i48/6111.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i48.6111