Extrahepatic portal vein thrombosis in children and adolescents: Influence of genetic thrombophilic disorders

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Dec 28, 2010 (publication date) through Nov 8, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 28, 2010; 16(48): 6123-6127
Published online Dec 28, 2010. doi: 10.3748/wjg.v16.i48.6123

Table 4 Frequency of thrombophilic disorders in children and adolescents with portal vein thrombosis n (%)

Study	Coagulation inhibitor protein deficit		Gene mutations
	PC	PS	*FVL*	*PTHR*	*MTHFR*
Dubuisson et al[13] (n = 20)	9 (45)	13 (65)	NP	NP	NP
Uttenreuther-Fischer et al[2] (n = 23)	NP	NP	2 (9)	NP	NP
Heller et al[1] (n = 24)	NP	NP	4 (17)	0	1 (4)
Pinto et al[12] (n = 14)	6 (43)	3 (21)	0	1 (7)	3 (21)
Current study (n = 31)	4 (13)	4 (13)	2 (6.5)	3 (9.7)	16 (67.7)

PC: Protein C; PS: Protein S; FVL: Factor V Leiden; PTHR: Prothrombin; MTHFR: Methylenetetrahydrofolate reductase; NP: Not provided.

Citation: Pietrobattista A, Luciani M, Abraldes JG, Candusso M, Pancotti S, Soldati M, Monti L, Torre G, Nobili V. Extrahepatic portal vein thrombosis in children and adolescents: Influence of genetic thrombophilic disorders. World J Gastroenterol 2010; 16(48): 6123-6127
URL: https://www.wjgnet.com/1007-9327/full/v16/i48/6123.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i48.6123