Prognostic values of chromosome 18q microsatellite alterations in stage II colonic carcinoma

Figure 2 Kaplan-Meier estimates of overall survival and disease-free survival among patients with stage II colon cancer according to microsatellite alteration. In our study, 18qLOH was significantly associated with reduced 5-year overall survival (P = 0.019) (A) and disease-free survival (P = 0.010) (B). High levels of microsatellite instability was moderately associated with improved 5-year overall survival during the follow-up period (P = 0.045) (C). LOH: Loss of heterozygosity; MSI-L: Low frequency microsatellite instability; MSI-H: High frequency of microsatellite instability; MSS: Microsatellite stable.