Prognostic values of chromosome 18q microsatellite alterations in stage II colonic carcinoma

Table 4 Five-year overall survival and disease-free survival after surgery in relation to microsatellite alteration in patients with stage II colon cancer

Parameter	Cases	5-yr overall survival (%)	P value	5-yr disease-free survival (%)	P value
18q-LOH			0.019		0.010
(+)	50	71.3		70.5
(-)	52	88.3		87.1
MSI			0.045		0.155
MSI-H	18	94.4		88.5
MSI-L/MSS	84	77.8		76.7

18q-LOH: Loss of heterozygosity at chromosome 18q; MSI: Microsatellite instability; MSI-L: Low frequency MSI; MSI-H: High frequency of MSI; MSS: Microsatellite stable.