Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 in patients with fatty liver diseases

Table 1 Scoring according to the histological features described by Kleiner et al[15]

Definition	Score
Steatosis
Grade
< 5%	0
5%-33%	1
33%-66%	2
> 66 %	3
Localization
Zone 3	0
Zone 2	1
Zone 1	2
Azonal	3
Panacinar	4
Type
Macrovesicles	In %
Microvesicles	In %
Mixed
Inflammation
Lobular
No foci	0
< 2 foci	1
2-4 foci	2
> 4 foci	3
Portal
No inflammation	0
Minimal	1
Mild	2
Moderate	3
Severe	4
Fibrosis
None	0
Mild/moderate	1
Periportal or perisinusoidal	2
Bridging fibrosis	3
Cirrhosis	4
Liver cell damage
Ballooning
None	0
Moderate	1
Severe	2
Mallory bodies
None	0
Moderate	1
Severe	2