Toll-like receptor 9 gene mutations and polymorphisms in Japanese ulcerative colitis patients

Table 7 Linkage disequilibrium among single nucleotide polymorphisms of Toll-like receptor 9 in ulcerative colitis cases and disease-free controls

SNPs		UC (n = 48)		Controls (n = 47)
		|D’|	r2	|D’|	r2
-1486 T/C	1174 A/G	1	1	1	1
-1486 T/C	2848 G/A	1	0.9522	1	0.9581
1174 A/G	2848 G/A	1	0.9522	1	0.9581

Lewontin’s D’ (|D’|) and the linkage disequilibrium coefficient r² between each pair of single nucleotide polymorphisms (SNPs) were examined by the expectation-maximization algorithm of SNPAlyze software. UC: Ulcerative colitis.