Protective effects of Lactobacillus plantarum against epithelial barrier dysfunction of human colon cell line NCM460

Figure 2 Lactobacillus plantarum inhibited the increased macromolecular permeability through NCM460 cells induced by enteroinvasive Escherichia coli (A) or enteropathogenic Escherichia coli (B). A: After infection with enteroinvasive Escherichia coli (EIEC) for 120 min, the relative intensity (RI) was significantly increased in the EIEC group compared with the control group. However, the RI was decreased significantly in Lactobacillus plantarum (L. plantarum) groups compared with the EIEC group; B: Similar results were obtained in the experiments with enteropathogenic Escherichia coli (EPEC). The data at each time point represent the mean ± SD obtained from four individual NCM460 monolayers. ^aP < 0.05 vs control group; ^cP < 0.05 vs corresponding EIEC or EPEC group.