Insulin like growth factor-1 increases fatty liver preservation in IGL-1 solution

Figure 4 Role of insulin like growth factor-1 on oxidative stress, mitochondrial damage and tumor necrosis factor-α release in steatotic liver. A: Hepatic malondialdehyde (MDA) levels after 120 min of reperfusion; B: Glutamate dehydrogenase (GLDH) activity levels after 120 min of normothermic reperfusion; C: Tumor necrosis factor-α (TNF-α) levels in perfusate after 120 min of normothermic reperfusion. Cont 2: Liver flushed and perfused ex vivo without cold preservation; IGL-1: Livers preserved in IGL-1 solution; IGL-1 + IGF-1: Livers preserved in IGL-1 with IGF-1. ^aP < 0.05 vs Cont 2, ^cP < 0.05 vs IGL-1. IGF-1: Insulin like growth factor-1; IGL-1: Institut georges lopez-1.