Insulin like growth factor-1 increases fatty liver preservation in IGL-1 solution

Figure 3 Beneficial effects of insulin like growth factor-1 on AKT and nitric oxide in steatotic liver graft preservation. A: Representative Western blottings of total and p-AKT at the top and densitometric analysis at the bottom after 24 h of cold storage and 120 min of normothermic reperfusion; B: Endothelial nitric oxide synthase (eNOS) protein levels in liver after 120 min of normothermic reperfusion. Representative Western blottings at the top and densitometric analysis at the bottom; C: Nitrite and nitrate levels after 120 min of normothermic reperfusion. Cont 2: Liver flushed and perfused ex vivo without cold preservation; IGL-1: Liver preserved in IGL-1 solution; IGL-1 + IGF-1: Livers preserved in IGL-1 with IGF-1. ^aP < 0.05 vs Cont 2, ^cP < 0.05 vs IGL-1. IGF-1: Insulin like growth factor-1; IGL-1: Institut georges lopez-1.