Chronic stress sensitizes rats to pancreatitis induced by cerulein: Role of TNF-α

Table 5 General biochemical assays in blood (mean ± SE)

Group	Glucose (mg/dL)	Urea (mg/dL)	Creatinine (mg/dL)	Calcium (mg/dL)	Proteins (g/dL)	AST (IU/L)	ALT (IU/L)	Hematocrit (%)
Stress (-)
Veh	139 ± 13	39 ± 4	0.48 ± 0.03	13.02 ± 0.57	8.51 ± 0.39	192 ± 21	88 ± 7	40 ± 5
Cer	153 ± 14	55 ± 4	0.65 ± 0.09	11.08 ± 0.48	7.46 ± 0.28	298 ± 32	155 ± 14	42 ± 4
Anti-TNF-α + Cer	148 ± 12	52 ± 5	0.67 ± 0.08	10.91 ± 0.70	7.51 ± 0.43	293 ± 20	149 ± 9	41 ± 5
Stress (+)
Veh	118 ± 11a	38 ± 5	0.50 ± 0.05	11.72 ± 0.61	8.48 ± 0.22	201 ± 26	95 ± 9	36 ± 5a
Cer	294 ± 26a	105 ± 9a	1.94 ± 0.50a	9.03 ± 0.33a	6.02 ± 0.19a	432 ± 35a	219 ± 19a	41 ± 3
Anti-TNF-α + Cer	189 ± 16c	73 ± 8c	1.14 ± 0.24c	9.63 ± 0.58	6.76 ± 0.35c	356 ± 29c	187 ± 19c	39 ± 4

^aP < 0.05 vs control-vehicle Stress (-) group;

^cP < 0.05 vs Stress (+) plus Cer group. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TNF-α: Tumor necrosis factor-α.