Chronic stress sensitizes rats to pancreatitis induced by cerulein: Role of TNF-α

Table 12 Histopathological score in stomach tissue (mean ± SE)

Group	Edema	Hemorrhage	Leukocyte infiltrate	Necrosis
Stress (-)
Veh	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00
Cer	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00
Anti-TNF-α + Cer	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00
Stress (+)
Veh	3.25 ± 0.14b	1.55 ± 0.08a	1.26 ± 0.19a	0.95 ± 0.06a
Cer	1.17 ± 0.08a	3.23 ± 0.29a	2.77 ± 0.16a	3.48 ± 0.32a
Anti-TNF-α + Cer	1.96 ± 0.17c	2.23 ± 0.15c	1.63 ± 0.05c	1.57 ± 0.12c

^aP < 0.05,

^bP < 0.01 vs control-vehicle Stress (-) group;

^cP < 0.05 vs Stress (+) plus Cer group. TNF-α: Tumor necrosis factor-α.