Chronic stress sensitizes rats to pancreatitis induced by cerulein: Role of TNF-α

Table 11 Energy metabolism in lung tissue (mean ± SE)

Group	ATP (μmol/mg protein)	ATP loss (%)	ADP/ATP ratio
Stress (-)
Veh	10.3 ± 0.5	0.0 ± 4.9	0.20 ± 0.03
Cer	10.0 ± 0.3	2.9 ± 2.9	0.22 ± 0.02
Anti-TNF-α + Cer	10.1 ± 0.4	1.9 ± 3.8	0.21 ± 0.03
Stress (+)
Veh	7.9 ± 0.7	25.5 ± 6.8	0.32 ± 0.05
Cer	3.6 ± 0.4a	66.0 ± 3.8a	0.72 ± 0.10a
Anti-TNF-α + Cer	6.7 ± 0.6c	36.8 ± 5.7c	0.49 ± 0.06c

^aP < 0.05 vs control-vehicle Stress (-) group;

^cP < 0.05 vs Stress (+) plus Cer group. TNF-α: Tumor necrosis factor-α.