Chronic stress sensitizes rats to pancreatitis induced by cerulein: Role of TNF-α

Table 1 Relevant parameters in serum (mean ± SE)

Group	Amylase (IU/L)	Lipase (IU/L)	TNF-α (pg/mL)	LDH (IU/L)
Stress (-)
Veh	402 ± 23	12 ± 2	BD	299 ± 21
Cer	569 ± 31	44 ± 3	BD	358 ± 23
Anti-TNF-α + Cer	572 ± 43	42 ± 5	BD	327 ± 27
Stress (+)
Veh	475 ± 21	21 ± 3	12 ± 2a	612 ± 41
Cer	3997 ± 226a	1793 ± 118a	42 ± 4a	3410 ± 218a
Anti-TNF-α + Cer	1895 ± 103c	714 ± 45c	16 ± 2c	1534 ± 121c

^aP < 0.05 vs control-vehicle Stress (-) group;

^cP < 0.05 vs Stress (+) plus Cer group. BD: Below detection limit; LDH: Lactate dehydrogenase; TNF-α: Tumor necrosis factor-α.