Absence of high amplitude propagating contractions in subjects with chronic spinal cord injury

Figure 1 Colonic motility index in relation to sleep. In both the non-spinal cord injury (SCI) and SCI groups, colonic motility index (MI) was significantly suppressed during the sleep phase compared to the pre-sleep phase (Pre-sleep vs Sleep, Control: 8.8 ± 1.9 vs 2.1 ± 0.9, P < 0.005; SCI: 2.4 ± 0.4 vs 0.2 ± 0.05, P < 0.001) and significantly increased after awakening from sleep (Sleep vs Arousal, Control: 2.1 ± 0.9 vs 16.5 ± 4.5, P < 0.001; SCI: 0.2 ± 0.03 vs 4.3 ± 0.8, P < 0.001). The MI during the pre-sleep and post-sleep phases was significantly lower in SCI subjects than in the non-SCI (non-SCI vs SCI, pre-sleep: 8.8 ±1.9 vs 2.4 ± 0.4, ^bP < 0.01; post-sleep: 16.5 ± 4.5 vs 4.3 ± 0.8, ^aP < 0.05).