Transient elastography: A non-invasive tool for assessing liver fibrosis in HIV/HCV patients

Table 2 Main hematological and virological parameters in the three study groups (mean ± SD)

	HIV (n = 71)	HCV (n = 53)	HIV/HCV (n = 66)
AST/ALT	1 ± 0.4	0.72 ± 0.28aj	0.9 ± 0.4
ALT (U/L), mean (range)	22 (7-113)fh	75 (16-551)	56.5 (9-280)g
AST (U/L), mean (range)	21 (11-56)fh	52.5 (18-209)	42.5 (14-281)
γGT (IU/L), mean (range)	33 (9-461)h	40.5 (10-479)i	76.5 (11-479)
Mean platelet count (109/L)	208 ± 59	184 ± 60	173 ± 61b
T-Chol (mg/dL)	201 ± 46	175 ± 28d	171 ± 48c
HDL-Chol (mg/dL)	44 ± 16	47 ± 12	44 ± 15
LDL Chol (mg/dL)	123 ± 32	108 ± 37.5	97 ± 40a
TG (mg/dL), mean (range)	137 (36-615)	103 (32-354)ej	118 (49-614)
HCV-RNA (IU/mL) > 700.000	-	29 (54.7)	44 (66.6)
HIV-RNA (copies/mL), mean (range)	6050 (50-700 000)	-	3300 (60-1 100 000)
HIV-RNA < 47 copies/mL (%)	44 (62)		45 (68.1)
CD4+ count (cells/μL), mean (range)	466.5 (17-1282)	-	446 (35-1445)
CD4+ < 200 cells/μL	381	-	382

^aP < 0.0001,

^bP < 0.002,

^cP < 0.001,

^dP < 0.004,

^eP < 0.02 vs human immunodeficiency virus (HIV);

^fP < 0.0001,

^gP < 0.02 vs hepatitis C virus (HCV);

^hP < 0.0001,

ⁱP < 0.01,

^jP < 0.05 vs HIV/HCV.

¹Data available in 66 patients;

²Data available in 56 patients. AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; γGT: γ-glutamyl transferase; T-Chol: Total cholesterol; HDL: High density lipoprotein; LDL: Low density lipoprotein; TG: Triglyceride.