Impact of endoscopy-based research on quality of life in healthy volunteers

Figure 1 Flow chart of the study. The multiple drug study with cross-over design was divided into 5 phases with test drug alone and in combination with low-dose aspirin during the second week. On days 0, 7 and 14 of each study, ten HV were asked to complete the questionnaires. Upper GI-endoscopy was performed on the same days with a 4-wk wash out period between the different phases.