Anti-inflammatory effects of Mangifera indica L. extract in a model of colitis

Figure 3 Hematoxylin and eosin staining of colons obtained from rats untreated or treated with dextran sulfate sodium (4%) and Mangifera indica L. . A: Control group: Received common water (100 ×); B: Exposed to 4% dextran sulfate sodium (DSS) and vehicle (100 ×); C: Co-treated with Mangifera indica L. (MIE) rectally (150 mg/kg) for 7 d, at the same time as DSS administration (100 ×); D: Treated with MIE (150 mg/kg) orally during 14 d prior to DSS administration, and co-administered rectally during DSS exposure (100 ×); E: Changes in histological score were assigned according to criteria defined in the Material and Methods. Each bar represents the mean ± SE of the different groups. ^aSignificant differences vs control group; ^cSignificant differences vs group A; P < 0.05.