Up-regulation of PIK3CA promotes metastasis in gastric carcinoma

Table 2 Difference of PIK3CA protein expression among normal gastric mucosa, primary, lymph node metastasis and distant metastasis in gastric cancer

Tissues	PIK3CA staining			Total	P
	0-1	2-4	5-6
Normal	10	0	0	10	0.036a
Primary	13	6	1	20	0.015b
Lymph node metastasis	5	3	7	15	0.044c
Distant metastasis	7	3	6	18	0.537d

^aP < 0.05, normal vs primary;

^bP < 0.05, primary vs lymph node metastasis;

^cP < 0.05, primary vs distant metastasis;

^dP > 0.05, lymph node metastasis vs distant metastasis, all by Mann-Whitney U test.