Peri-nuclear antibodies correlate with survival in Greek primary biliary cirrhosis patients

Table 3 Comparison of histological parameters between anti-nuclear envelope antibody positive, gp210 negative, and anti-nuclear envelope antibody negative patients n (%)

	Histological parameters		P value
	Gp210 negative (n = 38)	ANEA negative (n = 78)
Fibrosis
1	7 (25.0)	22 (40.7)	0.009
2	8 (28.6)	22 (40.7)
3	13 (48.4)	10 (18.6)
Portal inflammation
1	5 (17.9)	22 (40.7)	0.018
2 + 3	23 (82.1)	32 (59.3)
Interface hepatitis
0 + 1	10 (35.7)	31 (57.4)	0.032
2 + 3	18 (64.3)	23 (42.6)
Intralobular inflammation
0	8 (28.6)	9 (16.7)	0.274
1	14 (50.0)	35 (64.8)
2	6 (21.4)	10 (18.5)
Proliferation of bile ductules
0	7 (25.0)	25 (46.3)	0.031
1	21 (75.0)	29 (53.7)
Epithelioid granuloma
0	19 (67.9)	39 (72.2)	0.342
1	9 (32.1)	15 (27.8)

ANEA: Anti-nuclear envelope antibody.