Peri-nuclear antibodies correlate with survival in Greek primary biliary cirrhosis patients

Table 2 Comparison of histological parameters between anti-nuclear envelope antibody positive and anti-nuclear envelope antibody negative patients n (%)

	Histological parameters		P value
	ANEA positive (n = 69)	ANEA negative (n = 78)
Fibrosis
1	10 (22.7)	22 (40.7)	0.008
2	17 (38.6)	22 (40.7)
3	17 (38.6)	10 (18.6)
Portal inflammation
1	8 (18.2)	22 (40.7)	0.008
2 + 3	36 (81.8)	32 (59.3)
Interface hepatitis
0 + 1	16 (36.4)	31 (57.4)	0.019
2 + 3	28 (63.6)	23 (42.6)
Intralobular inflammation
0	11 (25)	9 (16.7)	0.359
1	19 (43.2)	35 (64.8)
2	14 (31.8)	10 (18.5)
Proliferation of bile ductules
0	12 (27.3)	25 (46.3)	0.027
1	32 (72.7)	29 (53.7)
Epithelioid granuloma
0	31 (70.5)	39 (72.2)	0.425
1	13 (29.5)	15 (27.8)

ANEA: Anti-nuclear envelope antibody.