Brief Article
Copyright ©2010 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 14, 2010; 16(38): 4823-4831
Published online Oct 14, 2010. doi: 10.3748/wjg.v16.i38.4823
Table 1 Characteristics of metastatic colorectal cancer patients treated with anti-epidermal growth factor receptor therapy (n = 43) n (%)
Clinico-pathological featureFrequency
Age (yr), median (range)64 (26-82)
Gender
Male26 (60.5)
Female17 (39.5)
Response
Progressive disease19 (44.2)
Partial response13 (30.2)
Stable disease11 (25.6)
EGFR
No Amplification/gene copy number gain4 (10.5)
Amplification/gene copy number gain34 (89.5)
K-RAS
Wild-type32 (74.4)
Mutation11 (25.6)
B-RAF
Wild-type38 (88.4)
Mutation5 (11.6)
PIK3CA
Wild-type41 (95.4)
Mutation2 (4.7)
PTEN
Negative12 (27.9)
Positive31 (72.1)
Overall survival time (mo), median (range)37.3 (3.6-180)
Progression-free survival (mo), median (range)16.0 (1-171)
Number of tumor buds, median (range)9.0 (1-44)
Tumor budding
High11 (25.6)
Low32 (74.4)