Mn-SOD and CuZn-SOD polymorphisms and interactions with risk factors in gastric cancer

doi:10.3748/wjg.v16.i37.4738

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Oct 7, 2010 (publication date) through Apr 18, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 7, 2010; 16(37): 4738-4746
Published online Oct 7, 2010. doi: 10.3748/wjg.v16.i37.4738

Table 7 Interaction of SOD1 G7958A and SOD2 Val16Ala for gastric cancer development

Genotype		HC (%)	GC (%)	¹OR (95% CI)	P
SOD1	SOD2	n = 147	n = 140	¹OR (95% CI)	P
GG	Val/Val	72 (49.0)	31 (22.1)	1.00
A/-	Val/Val	50 (34.0)	54 (38.6)	2.54 (1.43-4.52)	0.002
GG	Ala/-	7 (4.8)	8 (5.7)	2.69 (0.89-8.14)	0.079
A/-	Ala/-	18 (12.2)	47 (33.6)	6.43 (3.20-12.91)	< 0.001

A/-: AA + AG; Ala/-: Ala/Val + Ala/Ala. ¹Adjusted for age, sex, OR, 95% CI and P values were calculated by logistic regression. HC: Healthy control; GC: Gastric cancer.

Citation: Yi JF, Li YM, Liu T, He WT, Li X, Zhou WC, Kang SL, Zeng XT, Zhang JQ. Mn-SOD and CuZn-SOD polymorphisms and interactions with risk factors in gastric cancer. World J Gastroenterol 2010; 16(37): 4738-4746
URL: https://www.wjgnet.com/1007-9327/full/v16/i37/4738.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i37.4738