Plasma miR-216a as a potential marker of pancreatic injury in a rat model of acute pancreatitis

Figure 3 Light micrographs of the pancreas at 0 h (A), 12 h (B), 24 h (C), 48 h (D) and 72 h (E) after arginine injection. A: Neither interstitial edema nor acinar cell necrosis is seen; B: Interstitial edema and slight cellular infiltration in the interstitium can be seen; C: The acinar structures are partially destroyed. Interstitial edema and inflammatory infiltrate are greater in degree than at 12 h; D: The acinar architecture is markedly disrupted; E: Most pancreatic acinar cells show signs of degeneration or necrosis. Adipose tissue can be seen in the interstitial spaces.