Lowered HGK expression inhibits cell invasion and adhesion in hepatocellular carcinoma cell line HepG2

Figure 5 Hepatocyte progenitor kinase-like kinase, matrix metalloproteinase-2, matrix metalloproteinase-9 and nuclear factor-κB expressions in HepG2 cells (Western blotting). A: Retrovirus mediating RNAi targeting of hepatocyte progenitor kinase-like kinase (RV-shHGK)-1 significantly inhibited matrix metalloproteinase (MMP)-2, MMP-9 and nuclear factor (NF)-κB in HepG2 cells. MMP-2 protein expression in each group (Western blotting); B: Densitometric analysis hepatocyte progenitor kinase-like kinase (HGK), MMP-2, MMP-9 and NF-κB protein expression in HepG2 cells infected with RV-shHGK-1 or RV-shHGK-C, respectively. ^aP < 0.05 vs HepG2 cells infected with RV-shHGK-C.