HOGG1 polymorphism in atrophic gastritis and gastric cancer after Helicobacter pylori eradication

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Sep 21, 2010 (publication date) through Sep 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2010; 16(35): 4476-4482
Published online Sep 21, 2010. doi: 10.3748/wjg.v16.i35.4476

Table 4 Odds ratios for association of genotypes and gastric cancer/atrophic gastritis

HOGG1 subtypes	Gastric cancer vs control		Atrophic gastritis vs control
HOGG1 subtypes	OR (95% CI)	Adjusted OR (95% CI)¹	OR (95% CI)	Adjusted OR (95% CI)¹
Ser/ser	1	1	1	1
Ser/Cys	0.96 (0.51-1.84)	1.29 (0.57-2.93)	1.76 (1.03-3.0)	2.05 (1.14-3.68)
Cys/Cys	1.1 (0.48-2.10)	1.22 (0.48-3.14)	2.38 (1.34-4.23)	2.76 (1.47-5.18)

¹Adjusted for age, gender, other risk factors such as alcohol and smoking. HOGG1: Human oxoguanine glycosylase 1; OR: Odds ratios.

Citation: Sun LM, Shang Y, Zeng YM, Deng YY, Cheng JF. HOGG1 polymorphism in atrophic gastritis and gastric cancer after Helicobacter pylori eradication. World J Gastroenterol 2010; 16(35): 4476-4482
URL: https://www.wjgnet.com/1007-9327/full/v16/i35/4476.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i35.4476