Evaluation of cross-reactive antibody response to HVR1 in chronic hepatitis C

Table 1 Percentages of amino acid sequence variation in 16 selected hypervariable region 1 (%)

	Percentages of amino acid sequence variation
	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
1	51.9	40.7	29.6	48.1	40.7	40.7	44.4	40.7	29.6	40.7	70.4	59.3	48.1	48.1	37.0
2	-	44.4	51.9	51.9	55.6	66.7	44.4	44.4	51.9	48.1	63.0	59.3	40.7	48.1	44.4
3		-	33.3	51.9	66.7	59.3	51.9	48.1	40.7	55.6	55.6	63.0	55.6	37.0	33.3
4			-	44.4	48.1	37.0	51.9	37.0	44.4	48.1	66.7	59.3	44.4	51.9	44.4
5				-	44.4	70.4	37.0	33.3	40.7	51.9	59.3	59.3	33.3	55.6	44.4
6					-	59.3	55.6	40.7	51.9	51.9	74.0	59.3	40.7	66.7	51.9
7						-	59.3	55.6	59.3	55.6	63.0	48.1	63.0	51.9	59.3
8							-	48.1	40.7	59.3	63.0	55.6	44.4	40.7	48.1
9								-	51.9	66.7	44.4	48.1	29.6	51.9	51.9
10									-	48.1	51.9	66.7	48.1	48.1	51.9
11										-	63.0	51.9	51.9	66.7	44.4
12											-	66.7	66.7	66.7	55.6
13												-	55.6	63.0	66.7
14													-	44.4	51.9
15														-	48.1

The Percentages of amino acid sequence variation are based upon manual calculation. Symbols for the hepatitis C virus isolates are the same as those of Figure 1.