Decreased serum essential and aromatic amino acids in patients with chronic pancreatitis

Table 1 Selected laboratory values in patients with chronic pancreatitis and control subjects (mean ± SD)

	Control	Chronic pancreatitis	Statistical significance
No. of patients	21	35
Age (yr)	34 ± 13	50 ± 10	< 0.01
Body weight (kg)	76 ± 4	64 ± 10	< 0.01
Body mass index (kg/m2)	25 ± 2.7	22 ± 3.4	< 0.01
Serum total protein (g/L)	76 ± 4	72 ± 8	< 0.05
Serum albumin (g/L)	46 ± 3.6	42 ± 8	< 0.05
Serum triacylglycerol (mg/dL)	107 ± 30	119 ± 43	NS
Serum cholesterol (mg/dL)	195 ± 26	175 ± 44	< 0.05
Glucose (mmol/L)	5 ± 0.64	7.7 ± 2.8	< 0.01
Insulin (μU/mL)	12 ± 5.2	9.1 ± 4.4	< 0.05
Homeostasis model assessment	2.7 ± 1.3	2.6 ± 1.6	NS
Leptin (ng/mL)	6.6 ± 2.9	3.9 ± 2.5	< 0.01
Hemoglobin (mg/dL)	15 ± 2.9	13 ± 1.8	< 0.01
Blood urea nitrogen (mg/dL)	11 ± 2.8	14 ± 6	NS
Creatinine (mg/dL)	0.9 ± 0.13	0.89 ± 0.22	NS
Serum amylase (U/L)	54 ± 31	65 ± 35	NS
Urine amylase (U/L)	174 ± 66	344 ± 336	< 0.05
Serum lipase (U/L)	28 ± 16	69 ± 75	< 0.05
Serum alanine aminotransferase (U/L)	21 ± 9	38 ± 38	< 0.05
Serum aspartate aminotransferase (U/L)	19 ± 5	41 ± 45	< 0.05
Serum alkaline phosphatase (U/L)	80 ± 28	104 ± 65	NS
Serum-glutamyl transpeptidase (U/L)	26 ± 14	112 ± 152	< 0.05

NS: Not significant.