Specific shRNA targeting of FAK influenced collagen metabolism in rat hepatic stellate cells

doi:10.3748/wjg.v16.i32.4100

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Aug 28, 2010 (publication date) through Jul 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2010; 16(32): 4100-4106
Published online Aug 28, 2010. doi: 10.3748/wjg.v16.i32.4100

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Figure 1 Expression of enhanced green fluorescent protein at 48 h after treatment (fluorescent images, original magnification × 200). A: Control group; B: Fibronectin group; C: Sofast group; D: HK group; E: Focal adhesion kinase (FAK) short hairpin RNA group. FAK short hairpin RNA plasmids were successfully transfected into hepatic stellate cells. The results from fluorescence microscopy and flow cytometry showed that the transfection efficiency was 40% at 48 h.

Citation: Dun ZN, Zhang XL, An JY, Zheng LB, Barrett R, Xie SR. Specific shRNA targeting of FAK influenced collagen metabolism in rat hepatic stellate cells. World J Gastroenterol 2010; 16(32): 4100-4106
URL: https://www.wjgnet.com/1007-9327/full/v16/i32/4100.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i32.4100