Gene therapy for liver regeneration: Experimental studies and prospects for clinical trials

Figure 2 Major cytokine and growth factor signals during liver regeneration. NF-κB: Nuclear factor-κB; TNF-α: Tumor necrosis factor-α; IL-6: Interleukin-6; EGF: Epidermal growth factor; TGF-α: Transforming growth factor α; VEGF: Vascular endothelial growth factor; FGF: Fibroblast growth factor; HB-EGF: Heparin-binding EGF-like growth factor; AR: Amphiregulin; C/EBP: CCAAT/enhancer-binding protein; HGF: Hepatocyte growth factor.