Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma

doi:10.3748/wjg.v16.i32.4089

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2010; 16(32): 4089-4094
Published online Aug 28, 2010. doi: 10.3748/wjg.v16.i32.4089

Table 2 Concordance of MUC2 and MUC5AC protein expression in colorectal tissues n (%)

Tissue	n	Positive cases		Concordance MUC2 vs MUC5AC	P¹
Tissue	n	MUC2	MUC5AC	Concordance MUC2 vs MUC5AC	P¹
NM	6	6 (100.00)	0 (0.00)	0 (0.00)	0.5662
HP	12	12 (100.00)	12 (100.00)	12 (100.00)	< 0.0001
LGD	15	15 (100.00)	15 (100.00)	15 (100.00)	< 0.0001
HGD	14	14 (100.00)	14 (100.00)	14 (100.00)	< 0.0001
CCA	26	12 (46.15)	8 (30.77)	4 (15.38)	-
MC	15	15 (100.00)	15 (100.00)	15 (100.00)	< 0.0001
SRCC	8	7 (87.50)	8 (100.00)	7 (87.50)	< 0.0001

¹Concordance of MUC protein expression in CCA vs other groups.

NM: Normal mucosa; HP: Hyperplastic polyp; LGD: Low-grade dysplasia; HGD: High-grade dysplasia; CCA: Conventional colorectal adenocarcinoma; MC: Mucinous carcinoma; SRCC: Signet-ring cell carcinoma.

Citation: Bu XD, Li N, Tian XQ, Li L, Wang JS, Yu XJ, Huang PL. Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma. World J Gastroenterol 2010; 16(32): 4089-4094
URL: https://www.wjgnet.com/1007-9327/full/v16/i32/4089.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i32.4089