Colorectal cancer screening: The role of CT colonography

Table 1 Results from major trials on a per-patient basis: sensitivity, specificity, positive and negative predictive values

Multicenter trials	All polyp size	Polyps (≥5 mm)	Polyps (≥6 mm)	Polyps (≥7 mm)	Polyps (≥8 mm)	Polyps (≥9 mm)	Polyps (≥10 mm)
Per patient sensitivity
ACRIN	N/A	65%	78%	84%	87%	90%	90%
IMPACT	N/A	N/A	85%	86%	88%	91%	91%
Munich	84%	91%	N/A	N/A	N/A	N/A	92%
Per patient specificity
ACRIN	N/A	89%	88%	87%	87%	86%	86%
IMPACT	N/A	N/A	88%	87%	86%	85%	85%
Munich	47%	93%	N/A	N/A	N/A	N/A	98%
Per patient PPV
ACRIN	N/A	45%	40%	35%	31%	25%	23%
IMPACT	N/A	N/A	62%	N/A	N/A	N/A	N/A
Munich	48%	N/A	70%	N/A	N/A	N/A	79%
Per patient NPV
ACRIN	N/A	95%	98%	99%	99%	99%	99%
IMPACT	N/A	N/A	96%	N/A	N/A	N/A	N/A
Munich	84%	N/A	98%	N/A	N/A	N/A	99%

Results are categorized according to polyp size. PPV: Positive predictive value; NPV: Negative predictive value; N/A: Not assessable.