Expression of protein S100A4 is a predictor of recurrence in colorectal cancer

Figure 1 Immunohistochemical expression of protein S100A4. A: Protein S100A4 expression in normal colorectal epithelium. In all normal colonic epithelium, protein S100A4 immunoreactivity was clearly absent at both cytoplasm and nucleus; B: Negative expression of protein S100A4 in colorectal cancer (CRC); C: Positive expression of protein S100A4 in CRC. Cytoplasm of cancer cells was diffusely stained brown (all at × 200 magnification).