Therapeutic implications of colon cancer stem cells

doi:10.3748/wjg.v16.i31.3871

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Aug 21, 2010 (publication date) through Nov 12, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 21, 2010; 16(31): 3871-3877
Published online Aug 21, 2010. doi: 10.3748/wjg.v16.i31.3871

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Figure 1 Therapeutic implication of cancer stem cells. The failure of current standard therapies in tumor eradication can be explained by assuming that colorectal cancer stem cells (CRC-SCs) are able to survive treatments leading to an only transitory clinical remission. Therapeutic strategies that specifically target the CRC-SC pool, by eliminating the self-renewing component of the tumor mass, could be more effective in eradicating the tumor and reducing the risk of relapse and metastasis.

Citation: Fabrizi E, Martino SD, Pelacchi F, Ricci-Vitiani L. Therapeutic implications of colon cancer stem cells. World J Gastroenterol 2010; 16(31): 3871-3877
URL: https://www.wjgnet.com/1007-9327/full/v16/i31/3871.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i31.3871