Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients

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Aug 21, 2010 (publication date) through Nov 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 21, 2010; 16(31): 3888-3896
Published online Aug 21, 2010. doi: 10.3748/wjg.v16.i31.3888

Table 8 Association between glucocorticoids therapy outcome and the haplotype GR_4

Haplotype	Cohortcomposition	Therapy success rate in wt carriers (success/no success)	Therapy success rate in het/hom variant carriers (success/ no success)	P-value	OR (CI)
GR_4 merged	All	0.682 (15/7)	0.4 (2/3)	0.326	3.214 (0.434-23.787)
	Male	0.733 (11/4)	NA (0/0)	NA	NA
	Female	0.571 (4/3)	0.4 (2/3)	1.000	2.000 (0.194-20.614)

NA: Not applicable (at least one cell box was counted as 0, OR and P not calculatable).

Citation: Mwinyi J, Wenger C, Eloranta JJ, Kullak-Ublick GA. Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients. World J Gastroenterol 2010; 16(31): 3888-3896
URL: https://www.wjgnet.com/1007-9327/full/v16/i31/3888.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i31.3888