Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients

Table 2 Predicted haplotypes found to be in best reconstruction for 181 inflammatory bowel diseases patients

Haplotype number1	Haplotype composition2	Absolute haplotype frequency	Relative haplotype frequency	Number of haplotypes not included3
	Reference: GGGATGGCCATGT	(n = 362)
GR_1	1111111111111	165	0.456
GR_24	1111112111211	90	0.249
GR_34	1111211111111	72	0.199	2
GR_44	1112111111111	8	0.022
GR_5	2211112111221	6	0.017
GR_6	1111112111212	4	0.011
GR_7	1111112111111	3	0.008
GR_8	1111111111211	2	0.006	1
GR_9	1111112121212	2	0.006
GR_10	1111221111111	2	0.006	2
GR_11	2211112111211	2	0.006	1
GR_12	1111111111212	1	0.003	1
GR_13	1111112211212	1	0.003
GR_14	1111211112111	1	0.003
GR_15	1111212111111	1	0.003
GR_16	1121111111111	1	0.003
GR_17	2211111111111	1	0.003	1

¹Haplotypes are arranged in the order of decreasing frequency;

²1 indicates the reference allele at a certain position, 2 indicates the variant allele;

³Number of haplotypes not included in the subsequent association analysis (steroid therapy outcome, tables 4, 7 and 8) due to likelihood values ≤ 0.95;

⁴Haplotype GR_2 corresponds to haplotype b, GR_3 corresponds to haplotype c and GR_4 corresponds to haplotype d in Figure 2.